Readings

Required

Kandel, Eric R., James H. Schwartz, and Thomas M. Jessell. Principles of Neural Science. 4th ed. New York, NY: McGraw-Hill, Health Professions Division, 2000. ISBN: 9780838577011 .

Becker, E. B., and A. Bonni. "Cell cycle regulation of neuronal apoptosis in development and disease." Prog Neurobiol 72, no. 1 (January 2004): 1-25.

Emsley, J. G., B. D. Mitchell, G. Kempermann, and J. D. Macklis. "Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells." Prog Neurobiol 75, no. 5 (April 2005): 321-41.

Gage, F. H. "Mammalian neural stem cells." Science 287, no. 5457 (February 25, 2000): 1433-8.

Hensch, T. K. "Critical period regulation." Annu Rev Neurosci, no. 27 (2004): 549-79.

Hyman, S. E., and R. C. Malenka. "Addiction and the brain: the neurobiology of compulsion and its persistence." Nat Rev Neurosci 2, no. 10 (October 2001): 695-703.

LeDoux, J. "The emotional brain, fear, and the amygdala." Cell Mol Neurobiol 23, no. 4-5 (October 2003): 727-38.

Lipton, S. A., and P. A. Rosenberg. "Excitatory amino acids as a final common pathway for neurologic disorders." N Engl J Med 330, no. 9 (March 3, 1994): 613-22.

Maren, S. "Neurobiology of Pavlovian fear conditioning." Annu Rev Neurosci, no. 24 (2001): 897-931.

Miller, R. H. "Regulation of oligodendrocyte development in the vertebrate CNS." Prog Neurobiol 67, no. 6 (August 2002): 451-67.

Mooney, R. "Sensitive periods and circuits for learned birdsong." Curr Opin Neurobiol 9, no. 1 (February 1999): 121-7.

Penn, A. A., and C. J. Shatz. "Brain waves and brain wiring: the role of endogenous and sensory-driven neural activity in development." Pediatr Res. 45, no. 4 Pt 1 (April 1999): 447-58.

Schwab, M. E. "Repairing the injured spinal cord." Science 295, no. 5557 (February 8, 2002): 1029-31.

Walsh, D. M., and D. J. Selkoe. "Deciphering the molecular basis of memory failure in Alzheimer's disease." Neuron 44, no. 1 (September 30, 2004): 181-93.

Optional

Arlotta, P., B. J. Molyneaux, J. Chen, J. Inoue, R. Kominami, and J. D. Macklis. "Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo." Neuron 45, no. 2 (January 20, 2005): 207-21.

Basch, M. L., M. I. Garcia-Castro, and M. Bronner-Fraser. "Molecular mechanisms of neural crest induction." Birth Defects Res C Embryo Today 72, no. 2 (June 2004): 109-23.

Botto, L. D., C. A. Moore, M. J. Khoury, and J. D. Erickson. "Neural-tube defects." N Engl J Med 341, no. 20 (November 11, 1999): 1509-19.

Clark, G. D. "The classification of cortical dysplasias through molecular genetics." Brain Dev 26, no. 6 (September 2004): 351-62.

Copp, A. J., N. D. Greene, and J. N. Murdoch. "The genetic basis of mammalian neurulation." Nat Rev Genet 4, no. 10 (October 2003): 784-93.

Dent, E. W., and F. B. Gertler. "Cytoskeletal dynamics and transport in growth cone motility and axon guidance." Neuron 40, no. 2 (October 9, 2003): 209-27.

Farlie, P. G., S. J. McKeown, and D. F. Newgreen. "The neural crest: basic biology and clinical relationships in the craniofacial and enteric nervous systems." Birth Defects Res C Embryo Today 72, no. 2 (June 2004): 173-89.

Goda, Y., G. W. Davis. "Mechanisms of synapse assembly and disassembly." Neuron 40, no. 2 (October 9, 2003): 243-64.

Grove, E. A., and T. Fukuchi-Shimogori. "Generating the cerebral cortical area map." Annu Rev Neurosci, no. 26 (2003): 355-80.

Hyman, S. E. "Brain neurocircuitry of anxiety and fear: implications for clinical research and practice." Biol Psychiatry 44, no. 12 (December 15, 1998): 1201-3.

Kiecker, C., A. Lumsden. "Compartments and their boundaries in vertebrate brain development." Nat Rev Neurosci 6, no. 7 (July 2005): 553-64.

Koman, K. "The Science of Hurt: Medical researchers and doctors work to close the "gates" on pain." Harv Mag 108, no. 2 (November 2005): 46-54.

Magavi, S. S., B. R. Leavitt, and J. D. Macklis. "Induction of neurogenesis in the neocortex of adult mice." Nature 405, no. 6789 (June 22, 2000): 951-5.

Molyneaux, B. J., P. Arlotta, T. Hirata, M. Hibi, and J. D. Macklis. "Fezl is required for the birth and specification of corticospinal motor neurons." Neuron 47, no. 6 (September 15, 2005): 817-31.

Mullor, J. L., P. Sanchez, and A. R. Altaba. "Pathways and consequences: Hedgehog signaling in human disease." Trends Cell Biol 12, no. 12 (December 2002): 562-9.

Porter, B. E., and G. Tennekoon. "Myelin and disorders that affect the formation and maintenance of this sheath." Ment Retard Dev Disabil Res Rev 6, no. 1 (2000): 47-58.

Schwarz, Thomas L. "Release of Neurotransmitters." Chapter 8 in Fundamental Neuroscience, edited by Larry R. Squire, Floyd E. Bloom, Susan K. McConnell, James L. Roberts, Nicholas C. Spitzer, and Michael J. Zigmond. 2nd ed. San Diego, CA: Academic Press, 2002. ISBN: 9780126603033 .

Stern, C. D. "Neural induction: old problem, new findings, yet more questions." Development 132, no. 9 (May 2005): 2007-21.

Yu, T. W., and C. I. Bargmann. "Dynamic regulation of axon guidance." Nat Neurosci 4 (November 2001): 1169-76. (Supplementary)