Session 4: Enzyme Kinetics and Enzyme Inhibition

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Lecture Topics

Session_4.jpg
  • Enzymatic Reactions and Chemically Catalyzed Reactions vs. Uncatalyzed Chemical Reactions
  • Inhibitors of Enzyme Reactions

Readings

  • Chapter 12: Enzyme Kinetics, Inhibition, and Control
    • Reaction Kinetics
    • Enzyme Inhibition
    • Control of Enzyme Activity

Lecture Notes

Problem Set & Solutions

Problem Solving Video: Problem Set 3, Question 2: Proteases: Mechanisms of inhibition

In this problem, Dr. Fedeles explores the mechanisms of inhibition enzymes, in this case, proteases. In particular, it deals with possible mechanisms of inhibition of Interleukin Converting Enzyme (ICE).

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